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Publications

_{Copyright Notice: Any articles made available for download are for personal use only. Any other use requires prior permission of the author and the copyright holder.}

| 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2005 | 2004 | 2002 | Patents |

2023

• Lintott M, Perry A. (2023) Straightforward synthesis of N-arylindoles via one-pot Fischer indolisation–indole N-arylation, RSC Advances, volume 13, no. 23, pages 15993-15997, DOI:10.1039/d3ra02658b. [PDF]

2022

• Hughes‐Whiffing CA, Perry A. (2022) Three Complementary One‐Pot Four‐Component Reaction Sequences for Rapid, General and Direct Spiropyran Synthesis, European Journal of Organic Chemistry, volume 26, no. 2, DOI:10.1002/ejoc.202201245. [PDF]

2021

• Curnow A, Magnussen A, Reburn C, Perry A, Wood M. (2021) Experimental investigation of a combinational iron chelating protoporphyrin IX prodrug for fluorescence detection and photodynamic therapy, Lasers in Medical Science, DOI:10.1007/s10103-021-03367-1.
• Hughes-Whiffing CA, Perry A. (2021) One-pot, three-component Fischer indolisation–N-alkylation for rapid synthesis of 1,2,3-trisubstituted indoles, Organic & Biomolecular Chemistry, volume 19, no. 3, pages 627-634, DOI:10.1039/d0ob02185g. [PDF]

2020

• Swinson H, Perry A. (2020) Three-component spiropyran synthesis via tandem alkylation-condensation, Tetrahedron, volume 76, no. 23, DOI:10.1016/j.tet.2020.131219.

2019

• Reburn C, Anayo L, Magnussen A, Perry A, Wood M, Curnow A. (2019) Experimental findings utilising a new iron chelating ALA prodrug to enhance protoporphyrin IX-induced photodynamic therapy, Proceedings of SPIE - The International Society for Optical Engineering, volume 11070, DOI:10.1117/12.2525819.
• Perry A. (2019) New mechanism, new chromophore: investigating the electrophilic behaviour of styrylindolium dyes, Org Biomol Chem, volume 17, no. 19, pages 4825-4834, DOI:10.1039/c9ob00641a. [PDF]
• Curnow A, Perry A, Wood M. (2019) Improving in vitro photodynamic therapy through the development of a novel iron chelating aminolaevulinic acid prodrug, Photodiagnosis Photodyn Ther, volume 25, pages 157-165, DOI:10.1016/j.pdpdt.2018.12.005. [PDF]

2018

• Brown AR, Green J, Moreman J, Gunnarsson L, Mourabit S, Ball J, Winter M, Trznadel M, Correia A, Hacker C. (2018) Cardiovascular Effects and Molecular Mechanisms of Bisphenol A and Its Metabolite MBP in Zebrafish, Environmental Science and Technology, DOI:10.1021/acs.est.8b04281.
• Perry A, Davis K, West L. (2018) Synthesis of stereochemically-biased spiropyrans by microwave-promoted, one-pot alkylation-condensation, Organic and Biomolecular Chemistry, volume 16, no. 39, pages 7245-7254, DOI:10.1039/c8ob01996g.
• Moreman J, Takesono A, Trznadel M, Winter MJ, Perry A, Wood ME, Rogers NJ, Kudoh T, Tyler CR. (2018) Estrogenic Mechanisms and Cardiac Responses Following Early Life Exposure to Bisphenol A (BPA) and Its Metabolite 4-Methyl-2,4-bis( p-hydroxyphenyl)pent-1-ene (MBP) in Zebrafish, Environ Sci Technol, volume 52, no. 11, pages 6656-6665, DOI:10.1021/acs.est.8b01095. [PDF]

2017

• Waters A, Torregrossa R, Gero D, Perry A, Wood ME, Whiteman M. (2017) RT01, A Novel Derivative of the Mitochondria-targeted Hydrogen Sulfide Donor AP39, Reversed Hyperglycaemia-induced Mitochondrial Dysfunction in Murine Brain Microvascular Endothelial Cells, FREE RADICAL BIOLOGY AND MEDICINE, volume 112, pages 157-158, DOI:10.1016/j.freeradbiomed.2017.10.242. [PDF]
• Perry A, Kousseff CJ. (2017) Synthesis and metal binding properties of N-alkylcarboxyspiropyrans, Beilstein Journal of Organic Chemistry, volume 13, pages 1542-1550, DOI:10.3762/bjoc.13.154.

2016

• Gero D, Torregrossa R, Waters A, Perry A, Wood ME, Whiteman M. (2016) Mitochondria-Targeted Hydrogen Sulfide Donors Protect Microvascular Endothelial Cells from Hyperglycaemia-Induced Metabolic Changes and Oxidative Damage, FREE RADICAL BIOLOGY AND MEDICINE, volume 100, pages S179-S179, DOI:10.1016/j.freeradbiomed.2016.10.473. [PDF]
• Perry A, Miles D. (2016) An off-the-shelf sensor for colourimetric detection of sulfide, Tetrahedron Letters, volume 57, no. 51, pages 5788-5793, DOI:10.1016/j.tetlet.2016.11.040.
• Gerő D, Torregrossa R, Perry A, Waters A, Le-Trionnaire S, Whatmore JL, Wood M, Whiteman M. (2016) The novel mitochondria-targeted hydrogen sulfide (H2S) donors AP123 and AP39 protect against hyperglycemic injury in microvascular endothelial cells in vitro, Pharmacol Res, volume 113, no. Pt A, pages 186-198, DOI:10.1016/j.phrs.2016.08.019. [PDF]

2015

• Perry A, Green SJ, Horsell DW, Homett SM, Wood ME. (2015) A pyrene-appended spiropyran for selective photo-switchable binding of Zn(II): UV-visible and fluorescence spectroscopy studies of binding and non-covalent attachment to graphene, graphene oxide and carbon nanotubes, TETRAHEDRON, volume 71, no. 38, pages 6776-6783, DOI:10.1016/j.tet.2015.07.035. [PDF]
• Whiteman M, Perry A, Zhou Z, Bucci M, Papapetropoulos A, Cirino G, Wood ME. (2015) Phosphinodithioate and Phosphoramidodithioate Hydrogen Sulfide Donors, Handb Exp Pharmacol, volume 230, pages 337-363, DOI:10.1007/978-3-319-18144-8_17. [PDF]
• Alexander BE, Coles SJ, Khan TF, Maliszewsi J, Perry A, Pitak MP, Whiteman M, Wood ME. (2015) Investigating the generation of hydrogen sulphide from the phosphinodithioate slow-release donor GYY4137: Novel products and experimental tools, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 47, pages S52-S53, DOI:10.1016/j.niox.2015.02.126. [PDF]
• Tomasova L, Pavlovicova M, Malekova L, Misak A, Kristek F, Grman M, Cacanyiova S, Tomasek M, Tomaskova Z, Perry A. (2015) Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels, Nitric Oxide - Biology and Chemistry, volume 46, pages 131-144, DOI:10.1016/j.niox.2014.12.012.
• Tomasova L, Pavlovicova M, Malekova L, Misak A, Kristek F, Grman M, Cacanyiova S, Tomasek M, Tomaskova Z, Perry A. (2015) Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels, Nitric Oxide, volume 46, pages 131-144, DOI:10.1016/j.niox.2014.12.012. [PDF]

2014

• Ferguson D, Perry A, Wood ME, Winyard PG, Whiteman M. (2014) Potentiation of Methyl Aminolevulinate (MAL)-Induced Photodynamic Therapy (PDT) Killing of Skin Cancer Cells by Mitochondria-Targeted Hydrogen Sulfide (H₂S) Donors, FREE RADICAL BIOLOGY AND MEDICINE, volume 76, pages S135-S135, DOI:10.1016/j.freeradbiomed.2014.10.222. [PDF]
• Gero D, Szczesny B, Perry A, Modis K, Wood ME, Szabo C, Whiteman M. (2014) Novel Mitochondria-Targeted Hydrogen Sulfide (H₂S) Donors AP39 and AP123 Attenuate Hyperglycaemia-Induced Oxidative Stress and Loss of Bioenergetics in Microvascular Endothelial Cells, FREE RADICAL BIOLOGY AND MEDICINE, volume 76, pages S118-S118, DOI:10.1016/j.freeradbiomed.2014.10.254. [PDF]
• Tomasova L, Misak A, Kristek F, Perry A, Wood ME, Ondrias K, Whiteman M. (2014) Effects of a Novel Triphenylphosphonium Derivatised Anethole Dithiolethione Hydrogen Sulfide (H₂S) Donor, AP39, on Cardiac Ion Channels and on Haemodynamic Parameters in Normotensive and Hypertensive Rats in Vivo, FREE RADICAL BIOLOGY AND MEDICINE, volume 76, pages S55-S55, DOI:10.1016/j.freeradbiomed.2014.10.429. [PDF]
• Hurst TE, Gorman RM, Drouhin P, Perry A, Taylor RJK. (2014) A direct C-H/Ar-H coupling approach to oxindoles, thio-oxindoles, 3,4-dihydro-1 H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines, Chemistry (Weinheim an der Bergstrasse, Germany), volume 20, no. 43, pages 14063-14073, DOI:10.1002/chem.201403917.
• Hurst TE, Gorman RM, Drouhin P, Perry A, Taylor RJK. (2014) A direct C-H/Ar-H coupling approach to oxindoles, thio-oxindoles, 3,4-dihydro-1 H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines, Chemistry, volume 20, no. 43, pages 14063-14073, DOI:10.1002/chem.201403917. [PDF]
• Szczesny B, Módis K, Yanagi K, Coletta C, Le Trionnaire S, Perry A, Wood ME, Whiteman M, Szabo C. (2014) AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro, Nitric Oxide - Biology and Chemistry, volume 41, pages 120-130, DOI:10.1016/j.niox.2014.04.008.
• Gero D, Szczesny B, Modis K, Yanagi K, Wood ME, Perry A, Szabo C, Whiteman M. (2014) Mitochondira-targeted hydrogen sulfide donors AP39 and AP123 attenuate hyperglycaemia-induced oxidative stress and loss of bioenergetics in microvascular endothelial cells, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 39, pages S22-S23, DOI:10.1016/j.niox.2014.03.072. [PDF]
• Whiteman M, Perry A, Wood ME. (2014) H₂S in inflammation: Time for resolution?, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 39, pages S3-S3, DOI:10.1016/j.niox.2014.03.012. [PDF]
• Le Trionnaire S, Perry A, Szczesny B, Szabo C, Winyard PG, Whatmore JL, Wood ME, Whiteman M. (2014) The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl) triphenylphosphonium bromide (AP39), MedChemComm, volume 5, no. 6, pages 728-736, DOI:10.1039/c3md00323j.
• Szczesny B, Módis K, Yanagi K, Coletta C, Le Trionnaire S, Perry A, Wood ME, Whiteman M, Szabo C. (2014) AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro, Nitric Oxide, volume 41, pages 120-130, DOI:10.1016/j.niox.2014.04.008. [PDF]

2013

• Whiteman M, Perry A, Le Trionnaire S, Whatmore JL, Ahmed T, Fox B, Kerr P, Haigh R, Winyard PG, Wood ME. (2013) Modulation of inflammatory and vascular signalling by novel slow release and mitochondria-targeted H₂S donors, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 31, pages S13-S13, DOI:10.1016/j.niox.2013.06.014. [PDF]
• Le Trionnaire S, Perry A, Whatmore JL, Wood ME, Whiteman M. (2013) Mitochondria-targeted hydrogen sulfide donors: A novel twist to an old "tail"?, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 31, pages S57-S57, DOI:10.1016/j.niox.2013.06.112. [PDF]
• Whatmore JL, Wolanska KI, Perry A, Wood ME, Whiteman M. (2013) Slow release hydrogen sulfide (H₂S) donors prevent hyperglycaemia-induced glycocalyx loss in retinal mirovascular endothelial cells, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 31, pages S59-S59, DOI:10.1016/j.niox.2013.06.116. [PDF]

2012

• Fox B, Holland T, Perry A, Wood ME, Whiteman M. (2012) Characterising the effect of novel slow-release H₂S donors on pro-inflammatory enzyme activity in human cartilage cells, FREE RADICAL BIOLOGY AND MEDICINE, volume 53, pages S44-S44, DOI:10.1016/j.freeradbiomed.2012.08.513. [PDF]
• Le Trionnaire S, Whatmore JL, Perry A, Wood ME, Whiteman M. (2012) Slow release H₂S donors protect human microvascular endothelial cells from oxidative stress induced cell death: Markedly increased potency by mitochondria-targetting, FREE RADICAL BIOLOGY AND MEDICINE, volume 53, pages S134-S135, DOI:10.1016/j.freeradbiomed.2012.08.281. [PDF]
• Le Trionnaire S, Perry A, Whatmore JL, Winyard PG, Wood ME, Whiteman M. (2012) Mitochondria-Targeted Slow Release Hydrogen Donors: A Novel Link to an Old 'tail'?, FREE RADICAL BIOLOGY AND MEDICINE, volume 53, pages S121-S121, DOI:10.1016/j.freeradbiomed.2012.10.300. [PDF]
• Fox B, Holland T, Perry A, Winyard PG, Wood ME, Whiteman M. (2012) Defining the Effect of Novel Slow-Release H₂S Donors on Pro-Inflammatory Mediators and Enzymes in Human Joint Cells, FREE RADICAL BIOLOGY AND MEDICINE, volume 53, pages S75-S76, DOI:10.1016/j.freeradbiomed.2012.10.226. [PDF]
• Wolanska K, Perry A, Wood ME, Chibber R, Whatmore J, Whiteman M. (2012) Hydrogen sulfide - a novel guardian of the endothelial glycocalyx?, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 27, pages S39-S39, DOI:10.1016/j.niox.2012.08.064. [PDF]
• Le Trionnaire S, Whatmore J, Perry A, Wood ME, Matthew W. (2012) Slow release H₂S donors protect human microvascular endothelial cells from oxidative stress induced cell death: Markedly increased potency by mitochondria-targeting, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 27, pages S40-S41, DOI:10.1016/j.niox.2012.08.068. [PDF]
• Fox B, Perry A, Winyard P, Wood ME, Whiteman M. (2012) Characterising the effect of novel slow-release H₂S donors on pro-inflammatory enzyme activity in human cartilage cells, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, volume 27, pages S40-S40, DOI:10.1016/j.niox.2012.08.066. [PDF]
• Yong QC, Cheong JL, Hua F, Deng LW, Khoo YM, Lee HS, Perry A, Wood M, Whiteman M, Bian JS. (2012) Erratum: Regulation of heart function by endogenous gaseous mediators-crosstalk between nitric oxide and hydrogen sulfide (Antioxidants and Redox Signaling (2011) 14 (2081-2091)), Antioxidants and Redox Signaling, volume 16, no. 7, DOI:10.1089/ars.2011.4488.

2011

• Le Trionnaire S, Whatmore J, Perry A, Wood ME, Whiteman M. (2011) Endogenous hydrogen sulphide (H₂S) and novel slow release H₂S donors protect human microvascular endothelial cells from oxidative stress-induced cell death, DIABETOLOGIA, volume 54, pages S489-S489. [PDF]
• Le Trionnaire S, Whatmore JL, Perry A, Wood ME, Whiteman M. (2011) Endogenous hydrogen sulfide (H2 S) and novel slow release H2S donors protect human endothelial cells from oxidative stress-induced cell death, JOURNAL OF HUMAN HYPERTENSION, volume 25, no. 10, pages 630-630. [PDF]
• Yong Q-C, Cheong JL, Hua F, Deng L-W, Khoo YM, Lee H-S, Perry A, Wood M, Whiteman M, Bian J-S. (2011) Regulation of heart function by endogenous gaseous mediators-crosstalk between nitric oxide and hydrogen sulfide, Antioxid Redox Signal, volume 14, no. 11, pages 2081-2091, DOI:10.1089/ars.2010.3572. [PDF]

2010

• Pugh DS, Klein JEMN, Perry A, Taylor RJK. (2010) Preparation of 3-alkyl-oxindoles by copper(II)-mediated C-H, Ar-H coupling followed by decarboxyalkylation, Synlett, no. 6, pages 934-938, DOI:10.1055/s-0029-1219392.
• Lubkoll J, Millemaggi A, Perry A, Taylor RJK. (2010) Tandem Horner-Wadsworth-Emmons/Heck procedures for the preparation of 3-alkenyl-oxindoles: The synthesis of Semaxanib and GW441756, Tetrahedron, volume 66, no. 33, pages 6606-6612, DOI:10.1016/j.tet.2010.03.018.
• Klein JEMN, Perry A, Pugh DS, Taylor RJK. (2010) First C-H activation route to oxindoles using copper catalysis, Org Lett, volume 12, no. 15, pages 3446-3449, DOI:10.1021/ol1012668. [PDF]
• Chopra M, Perry A, Hodgkinson A, Wood ME, Whiteman M. (2010) Contrasting Effects of 'Fast' and 'Slow' Releasing H₂S Donors on β Cell Viability in the Diabetic Milieu, FREE RADICAL BIOLOGY AND MEDICINE, volume 49, pages S43-S43, DOI:10.1016/j.freeradbiomed.2010.10.091. [PDF]

2009

• Nelson A, Bone H, Damiano M, Welham M, Bartlett S, Perry A, Cordier CJ, Warriner S, Leach SG, Morton D. (2009) Exploring biologically-relevant chemical space with macrocyclic ligands, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, volume 238. [PDF]
• Bone HK, Damiano T, Bartlett S, Perry A, Letchford J, Ripoll YS, Nelson AS, Welham MJ. (2009) Involvement of GSK-3 in Regulation of Murine Embryonic Stem Cell Self-Renewal Revealed by a Series of Bisindolylmaleimides, Chemistry and Biology, volume 16, no. 1, pages 15-27, DOI:10.1016/j.chembiol.2008.11.003.
• Millemaggi A, Perry A, Whitwood AC, Taylor RJK. (2009) Telescoped enolate arylation/HWE procedure for the preparation of 3-alkenyl-oxindoles: The first synthesis of soulieotine, European Journal of Organic Chemistry, no. 18, pages 2947-2952, DOI:10.1002/ejoc.200900294.
• Perry A, Taylor RJK. (2009) Oxindole synthesis by direct C-H, Ar-H coupling, Chem Commun (Camb), no. 22, pages 3249-3251, DOI:10.1039/b903516h. [PDF]

2008

• Edwards MG, Kenworthy MN, Kitson RRA, Perry A, Scott MS, Whitwood AC, Taylor RJK. (2008) The preparation of α-alkylidene-γ-butyrolactones using a telescoped intramolecular Michael/Olefination (TIMO) sequence: Synthesis of (+)-paeonilactone B, European Journal of Organic Chemistry, no. 28, pages 4769-4783, DOI:10.1002/ejoc.200800558.
• McAllister GD, Perry A, Taylor RJK. (2008) Diaziridines and diazirines, Comprehensive Heterocyclic Chemistry III, 539-557.

2007

• Hodgson R, Kennedy A, Nelson A, Perry A. (2007) Synthesis of 3-sulfonyloxypyridines:: Oxidative ring expansion of α-furylsulfonamides and N→O sulfonyl transfer, SYNLETT, no. 7, pages 1043-1046, DOI:10.1055/s-2007-973875. [PDF]

2005

• Kennedy A, Nelson A, Perry A. (2005) A general, two-directional approach to aza-C-(1 → 1)-linked disaccharide mimetics, Chemical Communications, no. 12, pages 1646-1648, DOI:10.1039/b417899h.
• Kennedy A, Nelson A, Perry A. (2005) Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives, Beilstein Journal of Organic Chemistry, volume 1, DOI:10.1186/1860-5397-1-2.

2004

• Kennedy A, Nelson A, Perry A. (2004) Highly diastereoselective addition of ketone enolates to N-sulfinyl imines: Asymmetric synthesis of syn- and anti-1,3-amino alcohol derivatives, Synlett, no. 6, pages 967-970, DOI:10.1055/s-2004-820050.

2002

• Armstrong SK, Cross RJ, Farrugia LJ, Nichols DA, Perry A. (2002) Semi-rigid bis-phosphane ligands for metallamacrocycle formation, European Journal of Inorganic Chemistry, no. 1, pages 141-151, DOI:10.1002/1099-0682(20021)2002:1<141::AID-EJIC141>3.0.CO;2-W.

Patents

• Whiteman ML, Wood ME, Perry A. Compounds for use in the treatment of plants, Patent Number: WO2012042227 A1, Europe, USA, Japan, 2012. [PDF]

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