Profile
Dr Lavinia Gambelli
Postdoctoral Research Associate
Telephone: 01392 727468
Extension: (Streatham) 7468
I am a Postdoctoral Research Associate within Bertram Daum's group at the Living Systems Institute.
Research
My scientific interests revolve around (cryo-)electron microscopy and microbiology.
In my postdoctoral projects I investigate archaeal surface layers (s-layers) using cryo-electron microscopy (i.e. cryo-electron tomography, subtomogram averaging, single particle analysis). S-layers are widespread features within anchaea and bacteria, and mediate many essential functions in these microorganisms. Structurally, an S-layer is a proteinaceous lattice and constitutes the outermost layer in the cell envelope. Understanding in great detail s-layer structures can help us finding an application for nanotechnology and drug delivery.
Career
2018-present Postdoctoral Research Associate at the Living Systems Institute, University of Exeter, United Kingdom
2014-2018 PhD research within the Microbiology department, Radboud University, Nijmegen, the Netherlands
Awards
2018 KIEM award from the KNVM (Koninklijke Nederlandse Vereniging voor Microbiologie / Royal Dutch Society for Microbiology) for the best first publication written by a young microbiologist (DOI: 10.1128/AEM.02186-17).
Publications
Gambelli L. Guerrero-Cruz S., Mesman R., Cremers G., Jetten M.J.M., Op den Camp H.J.M., Kartal B., Lueke C., van Niftrik L., (2018). Community composition and ultrastructure of a nitrate-dependent anaerobic methane-oxidizing enrichment culture. App. Environ. Microbiol. DOI: 10.1128/AEM.02186-17
Gambelli L., Cremers G., Mesman, R., Guerrero, S., Dutilh B., Jetten M.S.M., Op den Camp H.J.M., van Niftrik L., (2016). Ultrastructure and viral metagenome of bacteriophages from an anerobic methane oxidizing Methylomirabilis bioreactor enrichment culture. Front. Microbiol. doi.org/10.3389/fmicb.2016.01740
Versantvoort W., Guerrero-Cruz S., Speth D.R., Frank J., Gambelli L., Cremers G., van Alen T., Jetten M.S.M., Kartal B., Op den Camp H.J.M., Reimann J., (2018). Comparative genomics of Candidatus Methylomirabilis species and description of Ca. Methylomirabilis Lanthanidiphila. Front. Microbiol. doi.org/10.3389/fmicb.2018.01672
Cremers G., Gambelli L., van Alen T., van Niftrik L., Op den Camp H.J.M., (2018). Bioreactor virome metagenomics sequencing using DNA spike-ins. PeerJ. DOI: 10.7717/peerj.4351