Dr Wolfram Moebius

I am interested in how the physical world shapes the dynamics in biological systems. Most often, it is the evolutionary dynamics I am investigating, but with collaborators I am also exploring the dynamics of individual molecules.

I lead a combined theoretical and experimental group and care deeply about the interaction between theory and experiment.

We use a range of theoretical approaches and simulation techniques to investigate evolution in abstract models and specific biological systems, from the infection of bacteria by their viruses to the evolution of resistance to pesticides.

Experimentally, our current model system of choice is bacteriophage T7 replicating on the bacterium E. coli, where we aim for experiments with explicit spatial structure that can be analysed and described quantitatively. In collaborations with colleagues, we investigate other systems, such as infection of the plant N. benthamiana with the plant virus TEV.

While much of our research aims to understand basic principles behind evolutionary dynamics in complex environments, we often perform our research with applications in mind.